4-Methoxyphenylboronic acid CAS NO.5720-07-0

1. Introduction of 4-Methoxyphenylboronic Acid

4-Methoxyphenylboronic Acid (CAS NO.5720-07-0) is a similar white solid powder and belongs to

1. Introduction of 4-Methoxyphenylboronic Acid

4-Methoxyphenylboronic Acid (CAS NO.5720-07-0) is a similar white solid powder and belongs to the Organometallic Reagents. Our 4-Methoxyphenylboronic Acid is ≥98%(HPLC) and can be manufactured 10 metric ton per year. Besides, its FOB price is 0-100000 USD/kilogram. Whereas, the min. order of it is 1 kilogram. It is in stock and can be sent from the beijing port. Furthermore, we'd like to receive from the L/C or T/T.

Others:

Formula:     C₇H₉BO₃
M.W.:       151.96
Feature:   Similar white powder,   mp 204-207°C

Appearance: Similar white solid powder
Assay: ≥98%(HPLC)
Packaging: 25KG/NET Fiber Drum with double lined plastic bag inside



2. Basic information of 4-Methoxyphenylboronic Acid

1) Properties:

(1)H-Bond Donor: 2; (2)H-Bond Acceptor: 3; (3)Rotatable Bond Count: 2; (4)Exact Mass: 152.064475; (5)MonoIsotopic Mass: 152.064475; (6)Topological Polar Surface Area: 49.7; (7)Heavy Atom Count: 11; (8)Complexity: 110; (9)Covalently-Bonded Unit Count: 1.

2) Descriptors of Structure

IUPAC Name: (4-methoxyphenyl)boronic acid
InChI: InChI=1S/C7H9BO3/c1-11-7-4-2-6(3-5-7)8(9)10/h2-5,9-10H,1H3
InChIKey: VOAAEKKFGLPLLU-UHFFFAOYSA-N
Canonical SMILES: B(C1=CC=C(C=C1)OC)(O)O

3) Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intravenous	200mg/kg (200mg/kg)		U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#00062,

4) Application

4-Methoxyphenylboronic Acid (CAS NO.5720-07-0) can be used in the manufacturing 1-methoxy-4-trans-styryl-benzene. And the reaction will take place at the temperature of 25 °C for 20 hours. It also needs Pd(OAc)₂, NaOAc, and the solvent of acetic acid. The yield of it is 97 %.



Reagent used for Suzuki-Miyaura cross-coupling reactions; Pd-catalyzed direct arylation; Highly effective synthesis using palladium-catalyzed arylation Suzuki-Miyaura cross-coupling in water; Palladium-catalyzed stereoselective Heck-type reaction; Tandem-type Pd(II)-catalyzed oxidative Heck reaction and intramolecular C-H amidation sequence; Copper-mediated ligandless aerobic fluoroalkylation of arylboronic acids with fluoroalkyl iodides; Ruthenium catalyzed direct arylation; Rh-catalyzed asymmetric conjugate addition.