China (Mainland)
3-Carboxyphenylboronic acid CAS NO.25487-66-5
- Min.Order: 1 Kilogram
- Payment Terms: L/C,T/T
- Product Details
Keywords
- 25487-66-5
Quick Details
- ProName: 3-Carboxyphenylboronic acid
- CasNo: 25487-66-5
- Molecular Formula: C7H7BO4
- Appearance: Similar white powder
- Application: intermediates
- DeliveryTime: in stock
- PackAge: 25KG/NET Fiber Drum with double lined ...
- Port: beijing
- ProductionCapacity: 10 Metric Ton/Year
- Purity: ≥98%(HPLC)
- Storage: Store in a cool, dry area. Keep contai...
- Transportation: NOT RESTRICTED
- LimitNum: 1 Kilogram
Superiority
1. Introduction of 3-Carboxyphenylboronic acid
3-Carboxyphenylboronic acid (CAS NO.25487-66-5) is a similar white powder and commonly used as
Details
1. Introduction of 3-Carboxyphenylboronic acid
3-Carboxyphenylboronic acid (CAS NO.25487-66-5) is a similar white powder and commonly used as a intermediate. Our product capacity of it is 10 metric ton per year and can provide its ≥98%(HPLC). It is in stock now and can be ordered from 1 kilogram. Its FOB price of this chemical is 0-100000 USD/kilogram. Whereas, we can accept the payment of L/C or T/T.
Our 3-Carboxyphenylboronic acid:
Appearance: Similar white powder
CAS NO.: 25487-66-5
Assay: ≥98%(HPLC)
Formula: C7H7BO4
M.W.: 165.94
Feature: Similar white powder, mp 243-247°C
Packaging: 25KG/NET Fiber Drum with double lined plastic bag inside.jpg "Package of 3-Carboxyphenylboronic acid")
Widely used in Suzuki coupling chemistry. It can be used for synthetic API.
2. Basic information of 3-Carboxyphenylboronic acid
1) Properties:
(1)H-Bond Donor: 3; (2)H-Bond Acceptor: 4; (3)Rotatable Bond Count: 2; (4)Exact Mass: 166.043739; (5)MonoIsotopic Mass: 166.043739; (6)Topological Polar Surface Area: 77.8; (7)Heavy Atom Count: 12; (8)Complexity: 171; (9)Covalently-Bonded Unit Count: 1.
2) Descriptors of Structure
IUPAC Name: 3-boronobenzoic acid
InChI: InChI=1S/C7H7BO4/c9-7(10)5-2-1-3-6(4-5)8(11)12/h1-4,11-12H,(H,9,10)
InChIKey: DBVFWZMQJQMJCB-UHFFFAOYSA-N
Canonical SMILES: B(C1=CC(=CC=C1)C(=O)O)(O)O
3) Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intravenous | 2560mg/kg (2560mg/kg) | "Boron, Metallo-Boron Compounds and Boranes," Adams, R.M., ed., New York, John Wiley & Sons, Inc., 1964Vol. -, Pg. 693, 1964. | |
| rat | LD50 | oral | > 3gm/kg (3000mg/kg) | Acta Physiologica Polonica. Vol. 12, Pg. 173, 1961. |
4) Application:
3-Carboxyphenylboronic acid (CAS NO.25487-66-5) can react with 3-bromo-pyridine to get 3-pyridin-3-yl-benzoic acid. This reaction which is a kind of Substitution//Suzuki reaction needs reagent aq. Na2CO3, catalytic agent Pd(PPh3)4 and solvent acetonitrile at temperature of 90 °C. The reaction time of it is 16 hours. The yield of it is 90%.
The detailed steps:
