2-Bromopyridine CAS NO.109-04-6

1. Introduction of 2-Bromopyridine

2-Bromopyridine (CAS NO.109-04-6) is a colorless to orange yellow transparent liquid and can be used as a

1. Introduction of 2-Bromopyridine

2-Bromopyridine (CAS NO.109-04-6) is a colorless to orange yellow transparent liquid and can be used as a intermediate. We can provide the 99%min(GC) 2-Bromopyridine and supply it 60 metric ton per year. The FOB price of this product is 0-100000 USD/kilogram. We are glad to receive the payment via L/C or T/T.

Other detailed information:

Appearance:Colorless to orange yellow transparent liquid
Assay: ≥99%(GC)
Moisture: ≤0.5%
CAS NO.: 109-04-6
Formula:  C₅H₄BrN                                                                                                                 
M.W.:   157.99
Feature:      Colorless to orange yellow transparent liquid, bp192-194℃(761mmHg), nD20 1. 5720,d420 1.650, fp54℃.Soluble completely in alcohol, benzene ether and pyridine. Color will turn darker in light and air sensitive.

2. Basic information of 2-Bromopyridine

1) Properties:

(1)XLogP3: 1.4; (2)H-Bond Donor: 0; (3)H-Bond Acceptor: 1; (4)Rotatable Bond Count: 0; (5)Exact Mass: 156.952711; (6)MonoIsotopic Mass: 156.952711; (7)Topological Polar Surface Area: 12.9; (8)Heavy Atom Count: 7; (9)Formal Charge: 0; (10)Complexity: 56; (11)Isotope Atom Count: 0; (12)Defined Atom Stereocenter Count: 0; (13)Undefined Atom Stereocenter Count: 0; (14)Defined Bond Stereocenter Count: 0; (15)Undefined Bond Stereocenter Count: 0; (16)Covalently-Bonded Unit Count: 1; (17)Feature 3D Acceptor Count: 1; (18)Feature 3D Hydrophobe Count: 1; (19)Feature 3D Ring Count: 1; (20)Effective Rotor Count: 0; (21)Conformer Sampling RMSD: 0.4; (22)CID Conformer Count: 1.

2) Physical Property

Physical Property	Value	Units	Temp (deg C)	Source
Melting Point	< 25	deg C		EXP
Boiling Point	194.8	deg C		EXP
pKa Dissociation Constant	0.9	(none)	25	EXP
log P (octanol-water)	1.42	(none)		EXP
Water Solubility	2.08E+04	mg/L	20	EXP
Henry's Law Constant	7.70E-06	atm-m3/mole	25	EST
Atmospheric OH Rate Constant	2.33E-13	cm3/molecule-sec	25	EST

3) Descriptors of Structure

InChI: InChI=1S/C5H4BrN/c6-5-3-1-2-4-7-5/h1-4H
InChIKey: IMRWILPUOVGIMU-UHFFFAOYSA-N
Canonical SMILES: C1=CC=NC(=C1)Br

4) Production of 2-Bromopyridine

2-Bromopyridine (CAS NO.109-04-6) can be obtained from the bromination of 2-Aminopyridine. You can see the detailed steps of this reaction as follows:



The yeild of this reaction is 83.8%.

5) Uses of 2-Bromopyridine

You can use this product in organic synthesis or pharmaceutical intermediates. Besides, it can be used in synthetic heart disease drugs such as Rythmodan in medical industry.